044 Simcyp Focused Workshop: Absorption I - February 21-25, 2022

Content
14 modules

Instructor
Kelly Turton

Released
03 Nov 2021

Price
£1,100.00

Description

Mechanistic oral absorption modelling and prediction of bioavailability for drug products incorporating inter-subject variability. Theory and applications of the Simcyp Advanced Dissolution, Absorption, and Metabolism (ADAM) Model.

Gut wall permeability and first-pass metabolism

Drug solubility, dissolution, precipitation and supersaturation

Oral drug absorption incorporating food effects

Bioavailability and the impact of physiology and dosage form including salts

Entero-hepatic recirculation

Inter-individual variability assessment

Application of the SIVA Toolkit to the modeling of in vitro experiments to confirm and/or estimate parameters for PBPK simulations with a case study; mechanistic modeling of dissolution and precipitation in USP 2, USP 4, serial dilution, transfer and biphasic systems.

Live Online Courses

There are no refunds for Live Online courses.  Certara retains the right to cancel the course 30 calendar days before the first session, in which case participants will receive a full refund.

Certificate

By completing/passing this course, you will attain the certificate Certificate of Completion - Absorption I

1.
Pre Course Questionnaire - Your experience, expectations and area of interest, an optional survey to take prior to the course.
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2.
Absorption I Agenda, February 21-25, 2022
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3.
Pre Workshop Reading List, A selection of publications related to the Simcyp Simulator and model-informed drug development.
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4.
Simcyp Simulator Download instructions (Amazon Workspaces download)
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5.
A beginners Introduction to the Simcyp Simulator
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6.
Slide Decks and Files for Loading - Absorption I
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7.
Hands-on Materials
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8.
Presentation Recordings - Absorption I
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9.

Absorption I: Session 1 WebEx (UK Time Zone)

10.

Absorption I: Session 2 WebEx (UK Time Zone)

11.

Absorption I: Session 3 WebEx (UK Time Zone)

12.

Absorption I: Session 4 WebEx (UK Time Zone)

13.

Absorption I: Office Hour and Conclusion of the course - WebEx (UK Time Zone)

14.
Survey, please complete for Certificate of completion
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