Description
September 30 - October 4, 2024 | ONLINE
Predicting and evaluating complex DDIs—application of the Simcyp Population-based Simulator to real-life cases.
Live Online Courses
There are no refunds for Live Online courses. Certara retains the right to cancel the course 30 calendar days before the first session, in which case participants will receive a full refund.
Objectives
Participants will learn good practices in combining data from both in vitro and clinical studies, whilst gaining experience in using such data within physiologically-based dynamic models to evaluate the DDI liability of drug candidates.
• Static vs. dynamic models (including discussion around regulatory guidance)
• Metabolic and transporter mediated DDIs
• Competitive inhibition, mechanism-based inhibition, induction, and suppression
• Complex DDIs involving combined interaction mechanisms and multiple inhibitors (including inhibitory metabolites)
• Importance of in vitro study design
• The role of non-hepatic metabolism in DDIs
• Use of parameter estimation and sensitivity analysis
• Optimal clinical study design
• Special populations—identification of individuals at risk of DDI
Certificate
By completing/passing this course, you will attain the certificate Certificate of Completion - DDI
User Accounts and Registrations
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Course Materials
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Cancellation Policy
Live Online Courses
There are no refunds for Live Online courses for cancellation or non-attendance by the participant. Certara retains the right to cancel the course 30 calendar days before the first session, in which case participants will receive a full refund.
e-Learning and Certifications
There are no refunds for e-Learning courses or certifications. Course expiration dates can be found on your Dashboard.
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Details
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